HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-Nitro-5-(octadecyloxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Nitro-5-(octadecyloxy)benzoic acid methyl ester | HCID 53698954 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-Nitro-5-(octadecyloxy)benzoic acid | HCID 19388943 | 62% |
Reaction Steps
A solution of 4.5 g of 3-nitro-5-(octadecyloxy)benzoic acid methyl ester and 4 ml of 6N NaOH in 200 ml of methanol and 50 ml of dioxane was stirred at reflux for 2.5 hours. The solvents were removed at reduced pressure and the residue was acidified with 1N HCl. The solid was filtered and recrystallized from methanol-water to give 2.7 g (62% yield, mp 101°-103°) of 3-nitro-5-(octadecyloxy) benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05298652 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-6f48a2f28709480da327d0c51a769222 |
| Source note | uspto-grants-1994_03 |