反应详情

A solution of 3,4-bis(tetradecyloxy)benzoic acid methyl ester (1.1 g, 2.0 mmol) and 1.6 ml (9.6 mmol) of 6N NaOH in 40 ml of methanol and 20 ml of dioxane was stirred at reflux for 17 hours. The solvents were removed at reduced pressure, the residue was acidified and the solid was filtered and recrystallized from methanol-THF-water to give 0.8 g (73% yield, mp 112°-113°) of 3,4-bis(tetradecyloxy)benzoic acid.

1. temperatureat reflux for 17 hours
2. customThe solvents were removed at reduced pressure
3. filtrationthe solid was filtered
4. customrecrystallized from methanol-THF-water