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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488285Generated: October 25, 2026

Palmitoyl chloride → N-(2-ethoxy-2-oxoethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycine ethyl ester

https://huagongshe.com/reaction/488285

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPalmitoyl chlorideHCID 8206—
ReactantN-(3,5-diaminobenzoyl)-N-(2-ethoxy-2-oxoethyl)glycine ethyl esterHCID 19091775—
ProductN-(2-ethoxy-2-oxoethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycine ethyl esterHCID 19091838—

Reaction Steps

The reaction of palmitoyl chloride with N-(3,5-diaminobenzoyl)-N-(2-ethoxy-2-oxoethyl)glycine ethyl ester as in Example 54 gave N-(2-ethoxy-2-oxoethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycine ethyl ester as an oil after chromatography on silica gel using 35% ethyl acetate-hexane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05298652
Source datasetuspto-grants-1994_03
ORD IDord-7223e8411b0a453fa879e8a191ae19ac
Source noteuspto-grants-1994_03