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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488287Generated: October 30, 2026

Sodium Hydroxide → N-(carboxymethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycine

https://huagongshe.com/reaction/488287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantN-(2-ethoxy-2-oxoethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycine ethyl esterHCID 19091838—
ProductN-(carboxymethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycineHCID 19091757—

Reaction Steps

Sodium hydroxide hydrolysis of N-(2-ethoxy-2-oxoethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycine ethyl ester as in Example 56 and recrystallization from methanol-water gave N-(carboxymethyl)-N-[3,5-bis(1-oxohexadecylamino)benzoyl]glycine, mp 129°-133°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05298652
Source datasetuspto-grants-1994_03
ORD IDord-6edd69e216da4d009484ad75c8ee23ae
Source noteuspto-grants-1994_03