1-Bromooctadecane → HCID 54176565, compound

Participants

Reaction Steps

A mixture of 2.0 g (14.7 mmol) of 3-hydroxyacetophenone, 5.9 g (17.6 mmol) of 1-bromooctadecane and 4.1 g (29.4 mmol) of anhydrous potassium carbonate in 35 ml of anhydrous DMF was stirred and heated at 80° for 45 hours. The solvent was removed under high vacuum, the residue was treated with 50 ml of 0.5 N HCl and the resultant solid was filtered and recrystallized from methanol to give 3.35 g (59% yield, mp 50°-52°) of 3-octadecyloxyacetophenone.

Provenance & Evidence