Sodium Hydroxide → HCID 19091779, compound

Participants

Reaction Steps

To 2.7 g (5.7 mmol) of 3,5-bis(decyloxy)-alpha-oxobenzeneacetic acid methyl ester in 400 ml of hot methanol was added 6.2 ml (6.2 mmol) of 1.0N NaOH and the solution was stirred at reflux for 5 minutes. The solvent was removed at reduced pressure, water and 10 ml of 1N HCl were added to the residue and the product was extracted with ethyl acetate. The dried extract was concentrated to give 2.55 g (97% yield) of 3,5-bis(decyloxy)-alpha-oxobenzeneacetic acid as a waxy solid.

Provenance & Evidence