Sodium Hydroxide → HCID 19091867, compound

HRID 488311Notes

Reaction equation

[OH-].[Na+].C([O:5][C:6](=[O:46])[CH2:7][N:8]([CH2:40][C:41]([O:43]CC)=[O:42])[C:9](=[O:39])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:13]=[CH:12][C:11]=1[O:31][CH2:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)C>>[C:41]([CH2:40][N:8]([C:9](=[O:39])[C:10]1[CH:15]=[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:13]=[CH:12][C:11]=1[O:31][CH2:32][C:33]1[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=1)[CH2:7][C:6]([OH:46])=[O:5])([OH:43])=[O:42]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 19091773HCID 19091773, compound

Product 1

HCID 19091867HCID 19091867, compoundYield 91%

Procedure

Sodium hydroxide hydrolysis of N-(2-ethoxy-2-oxoethyl)-N-[5-(tetradecyloxy)-2-(phenylmethoxy)benzoyl]glycine ethyl ester under conditions described in Example 81 gave N-(carboxymethyl)-N-[5-(tetradecyloxy)-2-(phenylmethoxy)benzoyl]glycine (91% yield, mp 71°-74°).

Sources & evidence

ORD record: ord-c9426210ec6e4e5499e7d288cc3ae841
Source dataset: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05298652

Reaction notes

Loading…