Sodium Hydroxide → 5-(Decyloxy)-2-(phenylmethoxy)benzoic acid

HRID 488314Notes

Reaction equation

HRID 488314 reaction equation
[OH-].[Na+].C[O:4][C:5](=[O:31])[C:6]1[CH:11]=[C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH:9]=[CH:8][C:7]=1[O:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:13]([O:12][C:10]1[CH:9]=[CH:8][C:7]([O:23][CH2:24][C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)=[C:6]([CH:11]=1)[C:5]([OH:31])=[O:4])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 537985285-(Decyloxy)-2-(phenylmethoxy)benzoic acid methyl ester

Product 1

HCID 190918315-(Decyloxy)-2-(phenylmethoxy)benzoic acidYield 88%

Procedure

Sodium hydroxide hydrolysis of 5-(decyloxy)-2-(phenylmethoxy) benzoic acid methyl ester under conditions described in Example 60 gave 5-(decyloxy)-2-(phenylmethoxy)benzoic acid (88% yield, mp 63°-65°).

Sources & evidence

ORD record
ord-c14ae217995d4e23973b632106222bc5
Source dataset
uspto-grants-1994_03
Patent number
US05298652

Reaction notes

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