Sodium Hydroxide → HCID 18951541, compound

HRID 488320Notes

Reaction equation

[OH-].[Na+].C[O:4][C:5](=[O:50])[C:6]1[CH:11]=[C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:9]=[CH:8][C:7]=1[O:31][CH2:32][CH2:33][CH2:34][O:35][C:36]1[CH:41]=[CH:40][C:39]([O:42][CH2:43][C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)=[CH:38][CH:37]=1>>[CH2:13]([O:12][C:10]1[CH:9]=[CH:8][C:7]([O:31][CH2:32][CH2:33][CH2:34][O:35][C:36]2[CH:41]=[CH:40][C:39]([O:42][CH2:43][C:44]3[CH:45]=[CH:46][CH:47]=[CH:48][CH:49]=3)=[CH:38][CH:37]=2)=[C:6]([CH:11]=1)[C:5]([OH:50])=[O:4])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 15233469HCID 15233469, compound

Product 1

HCID 18951541HCID 18951541, compoundYield 88%

Procedure

Sodium hydroxide hydrolysis of 5-(octadecyloxy)-2-[3-[4-(phenylmethoxy)phenoxy]propoxy]benzoic acid methyl ester under conditions described in Example 60 gave 5-(octadecyloxy)-2-[3-[4-(phenylmethoxy)phenoxy]propoxy]benzoic acid (88% yield, mp 92°-95°).

Sources & evidence

ORD record: ord-d0c68a10b7634ee0890e26e83937bc0f
Source dataset: uspto-grants-1994_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05298652

Reaction notes

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