Sodium Hydroxide → 5-[(12-Phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoic acid

HRID 488329Notes

Reaction equation

HRID 488329 reaction equation
[OH-].[Na+].C[O:4][C:5](=[O:40])[C:6]1[CH:11]=[C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][O:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:9]=[CH:8][C:7]=1[O:32][CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>>[O:25]([CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][O:12][C:10]1[CH:9]=[CH:8][C:7]([O:32][CH2:33][C:34]2[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=2)=[C:6]([CH:11]=1)[C:5]([OH:40])=[O:4])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 539298605-[(12-Phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoic acid methyl ester

Product 1

HCID 190918325-[(12-Phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoic acidYield 94%

Procedure

Sodium hydroxide hydrolysis of 5-[(12-phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoic acid methyl ester using conditions described in Example 60 gave 5-[(12-phenoxydodecyl)oxy]-2-(phenylmethoxy)benzoic acid (94% yield, mp 85°-87° ).

Sources & evidence

ORD record
ord-c5345d09ca1542a9b4e47d47477abbca
Source dataset
uspto-grants-1994_03
Patent number
US05298652

Reaction notes

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