Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48841Generated: October 28, 2026

Ethyl bromoacetate → {4-[2-(Benzylcarbamoyl-methyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl]-2-methoxy-phenoxy}-acetic acid ethyl ester

https://huagongshe.com/reaction/48841

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromoacetateHCID 7748—
Reactant2-[1-(4-hydroxy-3-methoxy-benzyl)6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamideHCID 22742675—
Product{4-[2-(Benzylcarbamoyl-methyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl]-2-methoxy-phenoxy}-acetic acid ethyl esterHCID 69759891—

Reaction Steps

prepared by reaction of 2-[1-(4-hydroxy-3-methoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide with ethyl bromoacetate

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703392B2
Source datasetuspto-grants-2004_03
ORD IDord-62516a17036f48cfbabbc8c008136bd0
Source noteuspto-grants-2004_03