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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 488436생성일: 2026년 10월 25일

Tributylphosphine → (E)-(2S)-2-Ethoxy-3-{4-[3-(4-furan-2-yl-phenyl)-3-phenyl-allyloxy]-phenyl}-propionic acid ethyl ester

https://huagongshe.com/reaction/488436

반응식

참여 물질

역할이름HCID투입량
반응물TributylphosphineHCID 13831—
반응물Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoateHCID 9816147—
반응물(E)-3-(4-furan-2-yl-phenyl)-3-phenyl-prop-2-en-1-olHCID 69774305—
용매BenzeneHCID 241—
생성물(E)-(2S)-2-Ethoxy-3-{4-[3-(4-furan-2-yl-phenyl)-3-phenyl-allyloxy]-phenyl}-propionic acid ethyl esterHCID 6977428553%

반응 단계

Reaction of (E)-3-(4-furan-2-yl-phenyl)-3-phenyl-prop-2-en-1-ol (475 mg, 1.72 mmol), tributylphosphine (0.63 ml, 2.58 mmol), (2S)-2-ethoxy-3-(4-hydroxy-phenyl)-propionic acid ethyl ester (451 mg, 1.89 mmol) and azodicarboxylic dipiperidide (650 mg, 2.58 mmol) in benzene in an identical manner to example 3 gave the title compound (450 mg, 53%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06972294B1
출처 데이터셋uspto-grants-2005_12
ORD IDord-70b21f79b1144ee8b263bf11ed02fd13
출처 메모uspto-grants-2005_12