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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488439Generated: October 29, 2026

Triphenylphosphine → 3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-phenyl}-2-ethoxy-propionic acid ethyl ester

https://huagongshe.com/reaction/488439

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriphenylphosphineHCID 11776—
ReactantDiethyl azodicarboxylateHCID 5462977—
ReactantEthyl 2-ethoxy-3-(4-hydroxyphenyl)propanoateHCID 11791243—
Reactant3,3-Bis-(4-bromophenyl)prop-2-en-1-olHCID 22270304—
Product3-{4-[3,3-Bis-(4-bromo-phenyl)-allyloxy]-phenyl}-2-ethoxy-propionic acid ethyl esterHCID 5418840756.2%

Reaction Steps

Reaction of 3,3-bis-(4-bromophenyl)-prop-2-en-1-ol (0.50 g, 1.36 mmol), triphenylphosphine (0.39 g, 1.50 mmol), 2-ethoxy-3-(4-hydroxy-phenyl)-propionic acid ethyl ester (0.39 g, 1.63 mmol) and diethy lazodicarboxylate (0.26 g, 1.51 mmol) in an identical manner to example 1 gave the title compound (450 mg, 56%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06972294B1
Source datasetuspto-grants-2005_12
ORD IDord-cba61c894ff44918856441ff78a8a1b9
Source noteuspto-grants-2005_12