HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylphosphine → HCID 69773863, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylphosphine | HCID 13831 | — |
| Reactant | Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate | HCID 9816147 | — |
| Reactant | HCID 67146538 | HCID 67146538 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 69773863 | HCID 69773863 | 90.3% |
Reaction Steps
Reaction of (E)-3-(4-bromophenyl)-3-phenyl-prop-2-en-1-ol (289 mg, 1.0 mmol), tributylphosphine (0.37 ml, 1.5 mmol), (2S)-2-ethoxy-3-(4-hydroxy-phenyl)-propionic acid ethyl ester (262 mg, 1.10 mmol) and azodicarboxylic dipiperidide (378 mg, 1.5 mmol) in benzene in an identical manner to example 3 gave the title compound (460 mg, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06972294B1 |
| Source dataset | uspto-grants-2005_12 |
| ORD ID | ord-e932d0a6369448a4a60c3ce6ad6168f9 |
| Source note | uspto-grants-2005_12 |