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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488467Generated: October 25, 2026

N-(3-ethynylphenyl)acetamide → 2-(3-Acetylamino-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester

https://huagongshe.com/reaction/488467

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-ethynylphenyl)acetamideHCID 2726447—
Reactantethyl 2-bromo-1,4-dimethyl-1H-imidazole-5-carboxylateHCID 13897513—
Product2-(3-Acetylamino-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl esterHCID 10268194—

Reaction Steps

The title compound, MS: m/e=326.8 (M+H+), was prepared in accordance with the general method of example 1b from N-(3-ethynyl-phenyl)-acetamide and 2-bromo-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06972299B2
Source datasetuspto-grants-2005_12
ORD IDord-5d7fdcec14f54bf692b945ee61aee2e2
Source noteuspto-grants-2005_12