HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Morpholin-4-ylmethyl-benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(morpholinomethyl)benzoic acid | HCID 703507 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Morpholin-4-ylmethyl-benzoyl chloride | HCID 13748961 | 105% |
Reaction Steps
2.33 g of α-morpholinoparatoluic acid are placed in 30 mL of CH2Cl2 and 3.76 g of SOCl2 are added. The not very homogenous solution is taken to reflux for 48 hours The white precipitate obtained is filtered, washed with CH2Cl2 and dried. 2.65 g of product is obtained (Yield=70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06972343B1 |
| Source dataset | uspto-grants-2005_12 |
| ORD ID | ord-0b598504e58e4679bead3b9058aa0db7 |
| Source note | uspto-grants-2005_12 |