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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488548Generated: October 30, 2026

2,4-Dimethoxy-3-phenylbenzaldehyde → (2E)-3-(2,4-Dimethoxy-3-phenylphenyl)prop-2-enoic acid

https://huagongshe.com/reaction/488548

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Dimethoxy-3-phenylbenzaldehydeHCID 21946143—
Reactant3-(3-Chloro-2,4-dimethoxyphenyl)prop-2-enoic acidHCID 68876786—
Product(2E)-3-(2,4-Dimethoxy-3-phenylphenyl)prop-2-enoic acidHCID 2194611096%

Reaction Steps

Compound 3c was synthesized from 2c in 96% yield using the procedure described for 3a. 1H NMR (DMSO-d6): δ 7.81 (d, J=8.8 Hz, 1H), 7.74 (d, J=16.0 Hz, 1H), 7.28–7.42 (m, 5H), 6.97 (d, J=8.8 Hz, 1H), 6.47 (d, J=16.0 Hz, 1H), 3.73 (s, 3H), 3.25 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06972339B2
Source datasetuspto-grants-2005_12
ORD IDord-4cf5d10d9abd47e29b9ec1debfe0ae86
Source noteuspto-grants-2005_12