HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-(trifluoromethyl)pyridine → 2-[1-(3,4-dimethoxy-benzyl)-6-methoxy-7-(5-trifluoromethyl-pyridin-2-yloxy)-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-(trifluoromethyl)pyridine | HCID 92342 | — |
| Reactant | 2-[1-(3,4-dimethoxy-benzyl)-7-hydroxy-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide | HCID 22742716 | — |
| Product | 2-[1-(3,4-dimethoxy-benzyl)-6-methoxy-7-(5-trifluoromethyl-pyridin-2-yloxy)-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide | HCID 22742572 | — |
Reaction Steps
prepared by reaction of 2-[1-(3,4-dimethoxy-benzyl)-7-hydroxy-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide with 2-chloro-5-trifluoromethyl-pyridine
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703392B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-4495c5ecd63742329da4d8845f287746 |
| Source note | uspto-grants-2004_03 |