Chloropyrazine → 2-[1-(3,4-dimethoxy-benzyl)-6-methoxy-7-(pyrazin-2-yloxy)-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide

Participants

Role	Name	HCID	Charge
Reactant	Chloropyrazine	HCID 73277	—
Reactant	2-[1-(3,4-dimethoxy-benzyl)-7-hydroxy-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide	HCID 22742716	—
Product	2-[1-(3,4-dimethoxy-benzyl)-6-methoxy-7-(pyrazin-2-yloxy)-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide	HCID 22742590	—

Reaction Steps

prepared by reaction of 2-[1-(3,4-dimethoxy-benzyl)-7-hydroxy-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(indan-1-yl)-acetamide with 2-chloro-pyrazine

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06703392B2
Source dataset	uspto-grants-2004_03
ORD ID	ord-7585679821ee45419a3aa02636c4d30c
Source note	uspto-grants-2004_03