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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 488651Generated: October 26, 2026

4-Bromo-2-ethylaniline → methyl (2Z)-2-(acetylamino)-3-(4-amino-3-isopropylphenyl)acrylate

https://huagongshe.com/reaction/488651

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-ethylanilineHCID 2801283—
ReactantBenzyl 2-(acetylamino)acrylateHCID 14382052—
Reactant4-Bromo-2-(propan-2-yl)anilineHCID 22271937—
Productmethyl (2Z)-2-(acetylamino)-3-(4-amino-3-isopropylphenyl)acrylateHCID 86585325—

Reaction Steps

The titled compound was prepared according to the method described in Example 1B substituting 2-acetylamino-acrylic acid methyl ester for 2-acetylamino-acrylic acid benzyl ester and 4-bromo-2-isopropylaniline for 4-bromo-2-ethylaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06972340B2
Source datasetuspto-grants-2005_12
ORD IDord-f3e6765daba3425f8d23bde943f32c61
Source noteuspto-grants-2005_12