HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl (2Z)-2-(acetylamino)-3-(4-amino-3-isopropylphenyl)acrylate → methyl N-acetyl-4-amino-3-isopropylphenylalaninate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl (2Z)-2-(acetylamino)-3-(4-amino-3-isopropylphenyl)acrylate | HCID 86585325 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | methyl N-acetyl-4-amino-3-isopropylphenylalaninate | HCID 69803103 | — |
Reaction Steps
methyl (2Z)-2-(acetylamino)-3-(4-amino-3-isopropylphenyl)acrylate (752 mg, 2.72 mmole) and 10% Pd/C (143 mg) stirred in ethanol (20 mL) under 1 atmosphere of hydrogen for 16 hours. The mixture was filtered through Celite and the filtrate was concentrated under reduced pressure to provide the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06972340B2 |
| Source dataset | uspto-grants-2005_12 |
| ORD ID | ord-40f018eea4dd47d8859cea3850569147 |
| Source note | uspto-grants-2005_12 |