反应详情

4-[[2-(dimethylhydrazono)cyclohexyl]methyl]-benzonitrile (6.1 g) (0.024 mol) and methyl iodide (35 ml) were stirred overnight at RT. The precipitate was filtered, washed twice with ethyl ether, then with EtOH, and finally with pentane. After drying, 2-[2-[(4-cyanophenyl)methyl]-cyclohexylidene]-1,1,1-trimethyl-hydrazinium iodide was obtained as a white solid (7.8 g, mp=175° C.). 1H NMR (CDCl3): 7.55 (2H, d), 7.25 (2H, d), 3.7 (9H, s), 3.3 (1H, m), 3.15 (1H, dd), 2.8-2.5 (3H, m), 2.2-1.4 (6H, m).

1. filtrationThe precipitate was filtered
2. washwashed twice with ethyl ether
3. customAfter drying