HCID 22269465, compound → HCID 22269445, compound

HRID 488951Notes

Reaction equation

HRID 488951 reaction equation
[CH2:1]([C:3]1[CH:32]=[CH:31][C:6]([C:7]([C:9]2[CH:17]=[C:16]([C:18](=O)[C:19]3[CH:24]=[CH:23][C:22]([CH2:25]C)=[CH:21][CH:20]=3)[C:12]([C:13]([OH:15])=[O:14])=[CH:11][C:10]=2[C:28]([OH:30])=[O:29])=O)=[CH:5][CH:4]=1)C.[H][H]>[Pd].C(O)(=O)C>[CH3:1][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][C:9]2[CH:17]=[C:16]([CH2:18][C:19]3[CH:24]=[CH:23][C:22]([CH3:25])=[CH:21][CH:20]=3)[C:12]([C:13]([OH:15])=[O:14])=[CH:11][C:10]=2[C:28]([OH:30])=[O:29])=[CH:31][CH:32]=1

Participants

5

Reactant 2

HCID 22269465HCID 22269465, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22269445HCID 22269445, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

A mixture of 21.1 grams of 4,6-bis(4 ethylbenzoyl)isophthalic acid, 350 mL of acetic acid, and 2.10 grams of 5% palladium on carbon (as a catalyst) was heated to 65° C. for 17 hours in an atmosphere of hydrogen at 270 kPa. The mixture was filtered through Celite™ diatomaceous earth filter agent to remove the catalyst. The resulting filtrate was concentrated in vacuo to give 4,6-bis(4-methylbenzyl)isophthalic acid.

Workup

  1. filtrationThe mixture was filtered through Celite™ diatomaceous earth
  2. filtrationfilter agent
  3. customto remove the catalyst
  4. concentrationThe resulting filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-b9217692a5f94a6586ab51a556a068aa
Source dataset
uspto-grants-2005_12
Patent number
US06974877B2

Reaction notes

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