反应详情

To a mixture of 143.3 grams of aluminum chloride and 400 mL of benzene was added 100 grams of 3,5,5-trimethylhexanoyl chloride over a 50 minute period at a rate such that the temperature did not exceed 35° C. When the addition was complete, the mixture was stirred at room temperature for three hours. The mixture was poured over 500 grams of ice and extracted with 400 mL of ethyl acetate. The organic phase was washed with brine, dried over magnesium sulfate, filtered and the solvent was removed in vacuo to give 3,5,5-trimethylhexanoylbenzene.

1. customdid not exceed 35° C
2. additionWhen the addition
3. extractionextracted with 400 mL of ethyl acetate
4. washThe organic phase was washed with brine
5. dry with materialdried over magnesium sulfate
6. filtrationfiltered
7. customthe solvent was removed in vacuo