HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 23387352, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-methoxybenzyl-2-(N-CBZ-L-valyloxy)-propionate | HCID 86603936 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 23387352 | HCID 23387352 | — |
Reaction Steps
To a solution of 4-methoxybenzyl-2-(N-CBZ-L-valyloxy)-propionate (7.8 g, 17.5 mmole) in dichloromethane (100 ml) was added trifluoroacetic acid (10 ml) and the solution was stirred for one hour at room temperature. The solution was evaporated under reduced pressure and the product was isolated by silica gel column chromatography. Yield: 5.0 g
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06974802B2 |
| Source dataset | uspto-grants-2005_12 |
| ORD ID | ord-df1574c717d144f6bb535b43b9c99f37 |
| Source note | uspto-grants-2005_12 |