2-Thiophenecarboxaldehyde → HCID 178469137, compound

HRID 489324Notes

Reaction equation

HRID 489324 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=O.[NH2:8][C:9]1[CH:13]=[CH:12][NH:11][N:10]=1.[F:14][C:15]([F:25])([F:24])[C:16](=O)[CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19]>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[C:17]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[C:16]([C:15]([F:14])([F:24])[F:25])[NH:8][C:9]2=[N:10][NH:11][CH:12]=[C:13]12

Participants

4

Reactant 3

HCID 73642-ThiophenecarboxaldehydeHCID 67793Ethyl 4,4,4-trifluoroacetoacetateHCID 178418806HCID 178418806, compound

Product 1

HCID 178469137HCID 178469137, compound

Procedure

The title compound was prepared from thiophene-2-aldehyde, 3-aminopyrazole and ethyl trifluoroacetoacetate in the same manner as in Example 1.

Sources & evidence

ORD record
ord-2a80ee81484d43a9b008b16a9ea1ee7a
Source dataset
uspto-grants-2005_12
Patent number
US06977262B2

Reaction notes

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