o-(Trifluoromethyl)benzaldehyde → HCID 178439489, compound
Reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=O.[NH2:13][C:14]1[CH:18]=[CH:17][NH:16][N:15]=1.O=[C:20]([CH2:27][CH2:28][CH3:29])[CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23]>>[CH2:27]([C:20]1[NH:13][C:14]2=[N:15][NH:16][CH:17]=[C:18]2[CH:5]([C:4]2[CH:7]=[CH:8][CH:9]=[CH:10][C:3]=2[C:2]([F:12])([F:11])[F:1])[C:21]=1[C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH2:28][CH3:29]Participants
4
Procedure
The title compound was prepared from 2-trifluoromethylbenzaldehyde, 3-aminopyrazole and ethyl 3-ketohexanoate in the same manner as in Example 25.
Sources & evidence
- ORD record
- ord-7d7253205bf74b27914d8eefa8816650
- Source dataset
- uspto-grants-2005_12
- Patent number
- US06977262B2
Reaction notes
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