Ethyl 3-oxohexanoate → HCID 178439505, compound
Reaction equation
[F:1][C:2]1[C:3]([CH3:10])=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=O.[NH2:11][C:12]1[CH:16]=[CH:15][NH:14][N:13]=1.O=[C:18]([CH2:25][CH2:26][CH3:27])[CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21]>>[F:1][C:2]1[C:3]([CH3:10])=[C:4]([CH:5]2[C:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[C:18]([CH2:25][CH2:26][CH3:27])[NH:11][C:12]3=[N:13][NH:14][CH:15]=[C:16]23)[CH:7]=[CH:8][CH:9]=1Participants
4
Procedure
The title compound was prepared from 3-fluoro-2-methylbenzaldehyde, 3-aminopyrazole and ethyl 3-ketohexanoate in the same manner as in Example 25.
Sources & evidence
- ORD record
- ord-e733cd8bbe2246dea1baac04552ad9a5
- Source dataset
- uspto-grants-2005_12
- Patent number
- US06977262B2
Reaction notes
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