2-Chloro-4-fluorobenzaldehyde → HCID 178439510, compound

HRID 489345Notes

Reaction equation

HRID 489345 reaction equation
[Cl:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH:4]=O.[NH2:11][C:12]1[CH:16]=[CH:15][NH:14][N:13]=1.O=[C:18]([CH2:25][CH2:26][CH3:27])[CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21]>>[Cl:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH:4]1[C:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[C:18]([CH2:25][CH2:26][CH3:27])[NH:11][C:12]2=[N:13][NH:14][CH:15]=[C:16]12

Participants

4

Reactant 3

HCID 1450242-Chloro-4-fluorobenzaldehydeHCID 238498Ethyl 3-oxohexanoateHCID 178418806HCID 178418806, compound

Product 1

HCID 178439510HCID 178439510, compound

Procedure

The title compound was prepared from 2-chloro-4-fluorobenzaldehyde, 3-aminopyrazole and ethyl 3-ketohexanoate in the same manner as in Example 25.

Sources & evidence

ORD record
ord-339618d5ab6a405aa9d5a35b329b9d0c
Source dataset
uspto-grants-2005_12
Patent number
US06977262B2

Reaction notes

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