2-Chloro-6-fluorobenzaldehyde → HCID 178439517, compound

HRID 489352Notes

Reaction equation

HRID 489352 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([F:10])[C:3]=1[CH:4]=O.[NH2:11][C:12]1[CH:16]=[CH:15][NH:14][N:13]=1.O=[C:18]([CH2:25][CH2:26][CH3:27])[CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21]>>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([F:10])[C:3]=1[CH:4]1[C:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[C:18]([CH2:25][CH2:26][CH3:27])[NH:11][C:12]2=[N:13][NH:14][CH:15]=[C:16]12

Participants

4

Reactant 3

HCID 678472-Chloro-6-fluorobenzaldehydeHCID 238498Ethyl 3-oxohexanoateHCID 178418806HCID 178418806, compound

Product 1

HCID 178439517HCID 178439517, compound

Procedure

The title compound was prepared from 2-chloro-6-fluorobenzaldehyde, 3-aminopyrazole and ethyl 3-ketohexanoate in the same manner as in Example 25.

Sources & evidence

ORD record
ord-27cc6783907e49bc8e3dffa7df0e12da
Source dataset
uspto-grants-2005_12
Patent number
US06977262B2

Reaction notes

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