HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester → Hydroxy-(hydroxy-phenyl-phosphinoyl)-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester | HCID 69524884 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | Hydroxy-(hydroxy-phenyl-phosphinoyl)-acetic acid | HCID 21897917 | 90% |
Reaction Steps
To a solution of (ethoxy-phenyl-phosphinoyl)-hydroxy-acetic acid ethyl ester (382 mg, 1.41 mmol) in 10 mL of 6 M HCl was heated to reflux overnight. The resulting mixture was concentrated to a minimum volume and lyophilized affording a pale yellow solid (274 mg, 90%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06706699B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-813ab4ec9a4442d3b025a4b348af6c3e |
| Source note | uspto-grants-2004_03 |