Methyl propionate → HCID 178436771, compound

HRID 489397Notes

Reaction equation

C(OC)(=O)CC.[Cl:7][C:8]1[C:15]([Cl:16])=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=O.[NH2:17][C:18]1[CH:22]=[CH:21][NH:20][N:19]=1.[C:23]([CH2:25][C:26](=O)[CH2:27][CH3:28])#[N:24]>>[C:23]([C:25]1[CH:10]([C:9]2[CH:12]=[CH:13][CH:14]=[C:15]([Cl:16])[C:8]=2[Cl:7])[C:22]2[C:18](=[N:19][NH:20][CH:21]=2)[NH:17][C:26]=1[CH2:27][CH3:28])#[N:24]

Participants

Reactant 4

HCID 11124Methyl propionate

HCID 357452,3-Dichlorobenzaldehyde

HCID 99203693-oxopentanenitrile

HCID 178418806HCID 178418806, compound

Product 1

HCID 178436771HCID 178436771, compound

Procedure

The title compound was prepared from methyl propionate, 2,3-dichlorobenzaldehyde, 3-aminopyrazole and 1-cyanobutan-2-one in the same manner as in Example 94.

Sources & evidence

ORD record: ord-42509306fcb64c1dab4e88384e7451e0
Source dataset: uspto-grants-2005_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06977262B2

Reaction notes

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