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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48941Generated: October 25, 2026

1-Ethynyl-3-methoxybenzene → 2-(3-Methoxy-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester

https://huagongshe.com/reaction/48941

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-3-methoxybenzeneHCID 640753—
Reactantethyl 2-bromo-1,4-dimethyl-1H-imidazole-5-carboxylateHCID 13897513—
Product2-(3-Methoxy-phenylethynyl)-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl esterHCID 9835890—

Reaction Steps

The title compound, MS: m/e=299.3 (M+H+) was prepared in accordance with the general method of example 1b from 2-bromo-3,5-dimethyl-3H-imidazole-4-carboxylic acid ethyl ester and 1-ethynyl-3-methoxy-benzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06706707B2
Source datasetuspto-grants-2004_03
ORD IDord-09be8da98a014be7805cd423e0d5b87f
Source noteuspto-grants-2004_03