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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 489410Generated: October 26, 2026

2-Chlorobenzaldehyde → 4-(2-chlorophenyl)-6-cyclopropyl-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

https://huagongshe.com/reaction/489410

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzaldehydeHCID 6996—
ReactantMethyl cyclopropanecarboxylateHCID 76122—
ReactantHCID 178418806HCID 178418806—
Product4-(2-chlorophenyl)-6-cyclopropyl-2,4-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrileHCID 178509367—

Reaction Steps

The title compound was prepared from methyl cyclopropanecarboxylate, 2-chlorobenzaldehyde and 3-aminopyrazole in the same manner as in Example 94.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06977262B2
Source datasetuspto-grants-2005_12
ORD IDord-eeea591103dd4e6cb37f9a62464d5948
Source noteuspto-grants-2005_12