Phenylacetylene → HCID 9814958, compound

HRID 48948Notes

Reaction equation

Br[C:2]1[N:6]([CH3:7])[C:5]([C:8]2[O:12][N:11]=[C:10]([CH:13]3[CH2:15][CH2:14]3)[N:9]=2)=[C:4]([CH3:16])[N:3]=1.[C:17]1([C:23]#[CH:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH:13]1([C:10]2[N:9]=[C:8]([C:5]3[N:6]([CH3:7])[C:2]([C:24]#[C:23][C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)=[N:3][C:4]=3[CH3:16])[O:12][N:11]=2)[CH2:15][CH2:14]1

Participants

Reactant 2

HCID 10821Phenylacetylene

HCID 22271744HCID 22271744, compound

Product 1

HCID 9814958HCID 9814958, compound

Procedure

The title compound, white solid, m.p. 120° C. and MS: m/e=305.2 (M+H+), was prepared from 5-(2-bromo-3,5-dimethyl-3H-imidazol-4-yl)-3-cyclopropyl-[1,2,4]oxadiazole and phenylacetylene in accordance with the general procedure of example 12c.

Sources & evidence

ORD record: ord-f88c52af00834a06b2d9be414132a793
Source dataset: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06706707B2

Reaction notes

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