S-(2-Aminoethyl) ethanethioate--hydrogen chloride (1/1) → HCID 87919653, compound

Participants

Reaction Steps

The coupling reaction of 13 (3.93 mmol) with S-acetylcysteamine hydrochloride is carried out according to method B described in the first synthetic route (example 1). After the various treatments, the expected compound is isolated by flash chromatography on a silica gel column (eluent: AcOEt/petroleum ether 60%). 14 is collected in the form of a colorless foam with a yield of 67%. Rf (AcOEt/petroleum ether, 6/4): 0.5. [α]D20=+9.3° (c 0.97, CHCl3).

Provenance & Evidence