HCID 22253953, compound → HCID 86593960, compound

Participants

Reaction Steps

The coupling reaction of 13 (3.93 mmol) with S-isobutyrylcysteamine hydrochloride is carried out according to method B described in the first synthetic route (example 1). After the various treatments, the expected compound is isolated by flash chromatography on a silica gel column (eluent: AcOEt/petroleum ether 65%). 15 is collected in the form of a colorless foam with a yield of 75%. Rf (AcOEt/petroleum ether, 5/5): 0.6. [α]D20=+7.9° (c 1.27, CHCl3).

Provenance & Evidence