HCID 22253943, compound → HCID 86593962, compound

Participants

Reaction Steps

The coupling reaction of 13 (3.93 mmol) of S-pivaloylcysteamine hydrochloride is carried out according to method B described in the first synthetic route (example 1). After the various treatments, the expected compound is isolated by flash chromatography on a silica gel column (eluent: AcOEt/petroleum ether 70%). 16 is collected in the form of a foam which, after trituration in hexane, provides a colorless powder (Yd=88%). Rf (CH2Cl2/ether, 6/4): 0.82. M.p.=85-88° C. [α]D20=+5.9° (c 1.02, CHCl3).

Provenance & Evidence