S-(2-Aminoethyl) benzenecarbothioate--hydrogen chloride (1/1) → HCID 56984260, compound

Participants

Reaction Steps

The coupling reaction of 13 (3.93 mmol) with S-benzoylcysteamine hydrochloride is carried out according to method B described in the first synthetic route (example 1). After the various treatments, the expected compound is isolated by flash chromatography on a silica gel column (eluent: AcOEt/petroleum ether 70%). 17 is collected in the form of a foam which, after trituration in hexane, provides a colorless foam (Yd=77%). Rf (CH2Cl2/ether, 6/4): 0.76. [α]D20=+7.8° (c 1.03, CHCl3).

Provenance & Evidence