HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylmethyl 3′,6′-dihydro[2,4′-bipyridine]-1′(2′H)-carboxylate → 2-(Piperidin-4-yl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylmethyl 3′,6′-dihydro[2,4′-bipyridine]-1′(2′H)-carboxylate | HCID 19029119 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 2-(Piperidin-4-yl)pyridine | HCID 10374750 | 88% |
Reaction Steps
The product from Example 36B was treated with 10% Pd/C (250 mg) at 60 psi and 50° C. for 40 hours to provide the title compound (150 mg, 88% yield). MS (DCI/NH3) m/e 163 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528134B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-acfb8778f735446faa6b5c74de95be20 |
| Source note | uspto-grants-2009_05 |