N-BOC-ethylenediamine → HCID 87598509, compound

HRID 490229Notes

Reaction equation

CO[C:3](=[C:10]([C:13]#[N:14])[C:11]#[N:12])[C:4]1[O:5][CH:6]=[CH:7][C:8]=1[CH3:9].[NH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:25])[O:20][C:21]([CH3:24])([CH3:23])[CH3:22]>>[C:13]([C:10]([C:11]#[N:12])=[C:3]([NH:15][CH2:16][CH2:17][NH:18][C:19]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:25])[C:4]1[O:5][CH:6]=[CH:7][C:8]=1[CH3:9])#[N:14]

Participants

Reactant 2

HCID 187201N-BOC-ethylenediamine

HCID 23033061HCID 23033061, compound

Product 1

HCID 87598509HCID 87598509, compound

Procedure

N-(2-{[2,2-dicyano-1-(3-methyl(2-furyl))vinyl]amino}ethyl)(tert-butoxy)carboxamide was synthesized in the same manner using [methoxy(3-methyl(2-furyl))methylene]methane-1,1-dicarbonitrile and tert-butyl N-(2-aminoethyl)carbamate. The NMR and ESI/MS data for this compound are shown below.

Sources & evidence

ORD record: ord-8bf0e3543b37485d9f03fb91f63f71fe
Source dataset: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07528140B2

Reaction notes

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