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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 490366Generated: October 28, 2026

(2H-1,3-benzodioxol-5-yl)boronic acid → 4-(4-Benzo[1,3]dioxol-5-yl-phenoxymethyl)-5-methyl-furan-2-carboxylic acid

https://huagongshe.com/reaction/490366

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2H-1,3-benzodioxol-5-yl)boronic acidHCID 2734371—
Reactant4-(4-Iodo-phenoxymethyl)-5-methyl-furan-2-carboxylic acid methyl esterHCID 58824157—
Product4-(4-Benzo[1,3]dioxol-5-yl-phenoxymethyl)-5-methyl-furan-2-carboxylic acidHCID 18444558—

Reaction Steps

Compound (28) was prepared from compound (20) and (3,4-methylenedioxyphenyl)-boronic acid by adapting the procedure of Example 24A. LC/MS System B; Rt=1.76 mins, m/z (ES−)=351 (M−H for C20H16O6)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07528157B2
Source datasetuspto-grants-2009_05
ORD IDord-69f237c5fa7142f1a50b72fa1c318186
Source noteuspto-grants-2009_05