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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 490382Generated: October 29, 2026

4-Fluorophenylboronic acid → 4-(4'-Fluoro-biphenyl-4-yloxymethyl)-5-methyl-furan-2-carboxylic acid

https://huagongshe.com/reaction/490382

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenylboronic acidHCID 285645—
Reactant4-(4-Iodo-phenoxymethyl)-5-methyl-furan-2-carboxylic acidHCID 18444654—
Product4-(4'-Fluoro-biphenyl-4-yloxymethyl)-5-methyl-furan-2-carboxylic acidHCID 18444571—

Reaction Steps

Compound (118) was prepared from compound (26) and (4-fluoro-phenyl)-boronic acid by adapting the procedure of Example 27B. LC/MS System B; Rt=1.79 mins, m/z (ES−)=325 (M−H for C19H15FO4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07528157B2
Source datasetuspto-grants-2009_05
ORD IDord-64a2793a28dc496f84cd59451be68aeb
Source noteuspto-grants-2009_05