Potassium Hydroxide → HCID 9903065, compound

Participants

Reaction Steps

2-[5,6-Dimethoxy-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-indol-1-yl]acetic acid is prepared by following the procedure described in example 88a, but using 1 g of tert-butyl 2-{5,6-dimethoxy-3-[1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]indol-1-yl}acetate and a solution of 73 ml of methanolic potassium hydroxide (0.1 g/ml; 1.78M). 0.701 g of 2-[5,6-dimethoxy-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)indol-1-yl]acetic acid is obtained, the characteristics of which are as follows:

Provenance & Evidence