HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → 2-Amino-5-fluoro-3-iodopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 2-Amino-5-fluoropyridine | HCID 2737701 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Amino-5-fluoro-3-iodopyridine | HCID 18455974 | 57.5% |
Reaction Steps
But using 5 g of 5-fluoropyridin-2-ylamine and 11.04 g of N-iodosuccinimide in 250 ml of glacial acetic acid. 6.1 g of 5-fluoro-3-iodopyridin-2-ylamine are thus obtained in the form of a solid, the characteristics of which are as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528147B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-515092439f1c47cab6c4711e987eb941 |
| Source note | uspto-grants-2009_05 |