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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 490508Generated: October 30, 2026

Potassium Hydroxide → HCID 67147678, compound

https://huagongshe.com/reaction/490508

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 67147480HCID 67147480—
ProductHCID 67147678HCID 6714767832.1%

Reaction Steps

[2-(5,6-Dimethoxy-1-methyl-1H-indol-3-yl)-1H-pyrrolo-[2,3-b]pyrid-4-ylmethyl]phenylethylamine is prepared as described in Example 179a starting with 0.16 g of [2-(5,6-dimethoxy-1-methyl-1H-indol-3-yl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyrid-4-ylmethyl]phenylethylamine instead of the [2-(5,6-dimethoxy-1-methyl-1H-indol-3-yl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyrid-4-ylmethyl](4-trifluoromethylsulfanylbenzyl)amine used in Example 179a and 1.2 cm3 of 5N potassium hydroxide. 0.038 g of [2-(5,6-dimethoxy-1-methyl-1H-indol-3-yl)-1H-pyrrolo[2,3-b]pyrid-4-ylmethyl]-phenylethylamine is obtained, the characteristics of which are as follows:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07528147B2
Source datasetuspto-grants-2009_05
ORD IDord-dd6367879c8348a1a6d2a53863394949
Source noteuspto-grants-2009_05