3-Cyanobenzene-1-sulfonyl chloride → HCID 67173961, compound

HRID 490569Notes

Reaction equation

HRID 490569 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[N:9]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[NH:8][C:7]2=[O:19])([O-])=O.[C:20]([C:22]1[CH:23]=[C:24]([S:28](Cl)(=[O:30])=[O:29])[CH:25]=[CH:26][CH:27]=1)#[N:21]>>[C:20]([C:22]1[CH:23]=[C:24]([S:28]([NH:1][C:4]2[CH:5]=[C:6]3[C:10](=[CH:11][CH:12]=2)[N:9]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[NH:8][C:7]3=[O:19])(=[O:30])=[O:29])[CH:25]=[CH:26][CH:27]=1)#[N:21]

Participants

3

Reactant 2

HCID 28013603-Cyanobenzene-1-sulfonyl chlorideHCID 9899794HCID 9899794, compound

Product 1

HCID 67173961HCID 67173961, compound

Procedure

This compound was obtained in analogy to example 32 (step B and C) using 5-nitro-1-phenyl-1,2-dihydro-indazol-3-one (prepared according to Combinatorial Chemistry and High Throughput Screening 2003, 6(5), 471-480) in step B and 3-cyanobenzenesulfonyl chloride (step C) as a light brown solid. MS (ESI+): 391.1[M+H]+).

Workup

  1. customThis compound was obtained in analogy to example 32 (step B and C)

Sources & evidence

ORD record
ord-adb04b6ef27547e0b20fe81146484c7b
Source dataset
uspto-grants-2009_05
Patent number
US07528158B2

Reaction notes

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