HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,4-Dichlorophenyl)piperazine → HCID 67548057, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,4-Dichlorophenyl)piperazine | HCID 93601 | — |
| Reactant | 1-Benzyl-4-[tert-butoxycarbonyl-(2,4-difluoro-benzyl)-amino]-pyrrolidine-2-carboxylic acid | HCID 67547470 | — |
| Product | HCID 67548057 | HCID 67548057 | 7% |
Reaction Steps
As described for Example 1f, 1-benzyl-4-[tert-butoxycarbonyl-(2,4-difluoro-benzyl)-amino]-pyrrolidine-2-carboxylic acid (60.0 mg, 0.134 mmol) was converted, using 1-(3,4-dichloro-phenyl)-piperazine instead of 2-piperazin-1-yl-benzonitrile, to the title compound (5.5 mg, 7.0%) as light yellow oil. MS m/e=559.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528136B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-856bb96f6b884328b845ba123533c13a |
| Source note | uspto-grants-2009_05 |