HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methoxyphenyl)piperazine → HCID 25121018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| Reactant | 1-Benzyl-4-[tert-butoxycarbonyl-(2,4-difluoro-benzyl)-amino]-pyrrolidine-2-carboxylic acid | HCID 67547470 | — |
| Product | HCID 25121018 | HCID 25121018 | 8.7% |
Reaction Steps
As described for Example 1f, 1-benzyl-4-[tert-butoxycarbonyl-(2,4-difluoro-benzyl)-amino]-pyrrolidine-2-carboxylic acid (60.0 mg, 0.134 mmol) was converted, using 1-(2-methoxy-phenyl)-piperazine instead of 2-piperazin-1-yl-benzonitrile, to the title compound (6.1 mg, 8.7%) as light yellow oil. MS m/e=521.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528136B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-5b4ea11fd5e34240806ebb4303b77d45 |
| Source note | uspto-grants-2009_05 |