Piperidine → 3-[5-(3-Diethylamino-propyl)-1H-indol-2-ylmethylene]-1,3-dihydro-indol-2-one

Participants

Reaction Conditions

Reaction Steps

A mixture of oxindole (26 mg, 0.19 mmol), 5-(3-diethylamino-propyl)-1H-indole-2-carbaldehyde (50 mg, 0.19 mmol) and piperidine(0.1 mL) in ethanol (1 mL) was heated in a sealed tube at 95° C. for 20 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give 13 mg (18%) of the title compound as an orange crystalline solid.

Provenance & Evidence